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Category: Public Engagement

An endocrinologist’s survival guide for live TV interviews

Published on 22/09/201616/11/2016 by Society for Endocrinology1 Comment

On the 5th of September 2016, news broke of a study which showed that taking Vitamin D supplements in addition to asthma medication cuts the risk of severe asthma attacks and the number of people needing steroid treatment. BBC World News contacted the Society for Endocrinology for expert comment on the story – here Honorary Associate Professor at the University of Warwick Rosemary Bland describes what she learned from the experience and leaves her top tips for dealing with the media.

 

My Tuesday started off pretty normally. It was around 10.30 in the morning and I had just returned from B&Q with a car full of compost and wood when my mobile rang. It was the press office at the Society for Endocrinology, wanting to know if I could do an interview for the BBC.

“Phone or radio?” I asked.

“Live TV,” they responded.

My instant reaction was to try and get out of it, thinking about my appearance as I was decorating the house. I gave some names for other experts in the field but I‘d barely had time to consider my lucky escape when a BBC producer rang. I guess they couldn’t contact my scapegoat!

It was exactly 10.41AM and I was asked if I could make it down to the London studio for 12.15PM. This is where the speedy nature of journalism and my first lesson really sunk in – what would be a stressful, logistical nightmare for most is just a regular request from the BBC.

London was out of the question. Luckily, Coventry has a BBC studio and a taxi was booked to pick me up at 11.45. The producer asked me a few questions to give the interviewer some background on the subject and she asked who I was and what I did so they could introduce me. Easy enough? Actually I found it difficult to decide.

I know a lot about vitamin D, but what did I know about this asthma study? Not much more than I’d seen on breakfast TV that morning. After a quick Google, I found all 71 pages of it. Here was the second lesson: you will not have time to do any homework in detail.

After absorbing what I could, I began to think about how the only thing I had to sort out now was myself (no hair and makeup in regional studios). However, remember the quote from Alien “in space, no one can hear you scream” well when on BBC World News ‘no one in the UK can see you’, so that was strangely comforting.

The third lesson was on how to dress. The microphone clips on, but the wires go inside your clothes. A blouse was easy; a dress would have been more difficult. In regional studios the camera only grabs your head and shoulders, so shoes don’t matter, but the white blouse was too pale (I’m wearing a coloured top next time). The cameraman kept in touch with London, but it’s weird not being able to see the interviewer. Try not to glance at yourself on the adjacent TV – it doesn’t help.

The next thing I knew, Philippa Thomas in London was introducing me to the hundreds of millions of viewers watching BBC World News around the world.

Like a politician might do, I had thought of three main points I wanted to get across, so I found myself answering her questions that way. Is that a good idea? I don’t know, but it gave me something to focus on and I found that helpful. Here is one of the most important lessons – think about what you want to say, don’t rely on the interviewer’s questions. This is especially important for public health messages where caution needs to be urged. Just try and remember that you are the expert. As it was World News, I also had to remember not to be UK specific – so not ‘the NHS’, but ‘health services’.

Whether it was the producer (get a phone number for your BBC contact just in case and text them afterwards to ask for the clip), Coventry staff, or the VERY calm man in London who talked into my ear, everyone at the BBC was efficient and helpful. Remember that they do this every day, and so if they have forgotten the little things that might be worrying you; just ask.

When I rang the press office to tell them I was doing it they asked if I was excited. At the time it didn’t feel like it, but after it was all over I think I was. Would I do it again? Probably, but I hope I get the call when I’m not decorating.

Categories Public Engagement

Hormones are not the new botox

Published on 02/09/201616/11/2016 by Society for EndocrinologyLeave a comment

Did you know that the thyroid gland, which regulates metabolism, “is often an area out of balance, and that [yoga] poses that stimulate the gland, such as shoulder stands, can help redress this”? Or that testosterone is the new botox? Neither did consultant endocrinologist Professor Maralyn Druce. Having had enough of the extraordinary claims echoed in the tabloids, she pens an open letter to the public in response.

 

Dear reader of newspapers, magazines and websites

Like you I am often interested in the latest developments in health and beauty; the many new things on the horizon that promise me happiness, youth or energy. Recently I have noticed a trend in the press for thinking about our hormones – our endocrine systems – as a route to improving our health and wellbeing.

I am a clinical endocrinologist, a doctor for people with health problems relating to the malfunctioning of hormone glands, and I can tell you that the many hormonal systems in the body are fascinating and complex. The complexity arises because these systems control and support functions for many different body functions, and they must be able to produce the correct amounts of the right hormones in response to the internal and external environment.

When you read some of these articles’ claims, you might be forgiven for thinking that your hormone glands are very fragile and that all sorts of measures need to be taken to ‘boost’ the production of certain hormones and support the limited supply of others. This is not true. Your thyroid gland in your neck produces thyroxine to control your metabolism, and it does so in response to another hormone called TSH. It does not need extra ‘boosting’ by complex poses in specially designed and costly yoga classes.

While yoga in general may be very positive for your health, mood, wellbeing or flexibility, there is no evidence that stretching the thyroid gland will change the amount of hormone it makes. Nor indeed is there any evidence, even if this were the case, that the proposed hormone boost would benefit you. Likewise, I’ve seen a lot of myths in the press concerning adrenal glands, which sit at the top of the kidneys and produce the hormone cortisol in response to both emotional and physical stress – helping the body to adjust and cope. Contrary to what you may read, your adrenal glands are not delicate bowls containing a small amount of precious cortisol that might run out. Different types of exercise will not cause your adrenal glands to ‘fatigue’ and run out of hormones – the adrenal glands are factories that make just the right amount of hormone to meet your body’s needs. There is also no evidence that you will benefit from special and often expensive supplements that are marketed to ‘support’ your hormones or your glands – a sensible diet and a healthy lifestyle are the only things that you need to do this, unless you have a specific illness that requires treatment.

We are also told that growth hormone is important for stronger bones and muscle growth, but there is no evidence that doing particular types of exercise to ‘boost’ levels has special benefits on bone strength or fitness over and above any other kind of fitness regime. In fact people with excessive levels of growth hormone actually suffer from a condition called acromegaly, which leads to a number of negative health effects. More is not always better.

For men who are healthy, the sex hormone testosterone varies across the day. Regular sleep results in regular cycles of hormonal change – and you don’t need special sleep products or sleep apps to help this happen, just some insight into how to live healthily.

If you are a woman trying to decide whether or not to use hormone replacement, for example when you reach the menopause, you should be able to weigh up the possible benefits against measured risks. Should you decide to opt for hormone replacement, this always needs to be discussed with your doctor. As yet there is no evidence that so-called ‘bioidentical’ or ‘natural’ hormone replacements are better for you, despite claims made to the contrary where potential profits are at stake. You should be very careful when you consider taking hormones that have not been properly safety-tested in clinical trials and whose long term side effects have not been measured or monitored. The risks are totally unknown.

Your hormones are doing a great job supporting the functions of your body, responding to your environment and coping with the effects of what is going on around and inside you. Our glands have been doing this for millennia. As yet there has been no evidence that the purchase of extra and expensive support systems – be they yoga poses, supplements or other interventions – will truly boost your hormone health.

Got an axe to grind with sensationalism about hormones in the media? Get in touch with your Society for Endocrinology press office and find out how we can support you.

 

P7 Maralyn Druce
Professor Maralyn Druce is Chair of the Society for Endocrinology Public Engagement Committee, and a Professor of Endocrine Medicine at Barts and the London NHS Trust.

 

Categories Membership, Public Engagement•Tags controversial, fact vs opinion, hormones, pseudo-science

The curious case of Caster Semenya: intersexed athletes and competitive advantage

Published on 18/08/201616/11/2016 by Society for Endocrinology3 Comments

Following the recent media coverage of Caster Semenya competing at the Rio Olympics 2016, we have republished an abridged version of Harriet Nerva’s essay on disorders of sexual development, which won the Society for Endocrinology Undergraduate Essay Prize in 2010. You can read the full version here.

Gender verification and sport are two terms which when put together provide a bang louder than any starting pistol. In August 2009, Caster Semenya an 18 year old South African female athlete won the 800m sprint in the World Championship in Athletics in a world-record time. Her muscular build and fast time fuelled rumours of hermaphroditism and levels of testosterone three times that of ‘normal’. She was ordered to take a gender verification test. The worldwide controversy that followed has forced athletic organisations to create new guidelines for intersexed athletes, also known as those with a disorder of sexual differentiation (DSD). These are still being decided as this essay is written.

So are you female or male? The answer may seem simple enough – except that is for the 1.7% of the population who are born intersexed, and, for any young budding intersexed athlete out there, the consequences may be far reaching.

Introduced in 1936, and used to catch male imposters in female sporting events, compulsory gender testing of female athletes was abolished in 1992, with organisations retaining the right to test anyone thought of as ‘suspicious’. Males and females have traditionally been separated in elite sport because of the competitive advantage that men are argued to possess. The advantage stems from biologically determined sex differences in physical characteristics such as height, body composition, muscle mass, endurance and cardiovascular capacity.

However gender testing was never meant to address the issue of intersexed athletes. There is no evidence that female athletes with DSDs have displayed any sport-relevant physical attributes which have not been seen in biologically normal female athletes. Why is Semenya being tested? The grounds for her testing and the test itself have not been clarified.

DSD or ‘intersex’ refers to the atypical appearance of the external genitalia at birth where they differ from the usual development of either sex and create difficulty in sex assignment. The DSDs can broadly be split into 3 groups. Firstly, disorders of chromosomal sex occur when there is nondisjunction of sex chromosomes during meiosis. Secondly in disorders of gonadal sex, chromosomal sex is normal but the differentiation of the gonads is abnormal.

Thirdly there are the disorders of phenotypic sex. Here the phenotypic sex is ambiguous or is completely in disagreement with chromosomal and gonadal sex. Female pseudohermaphrodites (virilised females) have a 46, XX karyotype and female gonads, but ambiguous or male external genetalia. Male pseuodohermaphrodites (undervirlised males) have a 46 XY karyotype and male gonads, but ambiguous or female external genetalia. A true hermaphrodite has both ovarian and testicular tissue, irrespective of karyotype. Internal genetalia may also be mixed and external genetalia may be male, female or ambiguous.

Methods of defining gender in sport have been notoriously controversial. In essence what gender verification tries to do is find a cut-off point between females and males. This is harder than it sounds – sex is not defined by one parameter, it is a complicated combination of many, but athletics bodies have broadly used chromosomal sex for differentiation. Do DSDs always result in competitive advantage and do they always affect chromosomal sex test results? What about all this testosterone rumoured to be flying around?

Whereas in men a testosterone dose-response relationship has been shown to exist in sport, in women this relationship has only been found in relation to ‘explosive performance’. This measurement of height and power output involves performing the lowering portion of a lift at normal speed while the lifting portion is performed as rapidly and forcefully as possible. The dose-response relationship found was weaker in women than in men. It has been argued that this is because of gender differences in skeletal muscle sensitivity to testosterone, but this has not been substantiated. Whether women show a dose response relationship across all sporting attributes (for example endurance) is unknown, possibly because there is a lack of data on the relationship between resting testosterone levels in elite competitors and neuromuscular performance. In 2006 Cardinal and Stone found that testosterone levels varied significantly in different athletic groups, with sprinters having the highest values for both men and women.

And what of Caster Semenya? If judged ineligible to compete as a woman, she would also be ineligible to compete as a man, and if she refuses to consent to treatment (and is not taking anabolic steroids), must she be allowed to compete as an intersexed athlete based in moral obligation of athletic organisations? Finally as these organisations move to open “centres of excellence” around the world that would be equipped to treat intersexed athletes with anything from hormone therapy to surgery (Handley, 2010), what is the role of endocrinologists? Torn between controlling athletic prowess and the best interest of the client, we have to ask how level the playing field can, and should, ever be.

Categories Public Engagement

Life after Brexit for UK scientists

Published on 13/07/201626/07/2016 by Society for EndocrinologyLeave a comment

 

Amber Abernethie.jpgThis year, I was lucky enough to attend my first parliamentary links day. The largest science event in the Houses of Parliament, this day is held to promote dialogue between parliament and the scientific community. Given the vote to leave the EU less than a week earlier, it couldn’t have been a more interesting time to attend!

The scientific community directly benefit from the EU in terms of funding, collaboration and free movement of people. It was therefore no surprise that this year’s event saw the biggest attendance in history. The event, opened by John Bercow MP (Speaker of the House of Commons), involved opening remarks from Jo Johnson (Minister for Universities and Science) and Nicola Blackwood (Chair of the Science and Technology Select Committee). Two panels then followed, and then final speeches were given by Lord O’Neill of Gately, Sir Venki Ramakrishnan, and Stephen Metcalfe MP. Bewildered scientists filled the room, all anxious about their now uncertain future, and all speakers tried their best to reassure us.

‘Nothing has changed overnight in legal terms’ said Jo Johnson. MPs agreed that we have a strong country with a resilient history, and are able to pull through. Our science in particular they say is world class, and this can be used to help in our recovery. Many speakers told of reassurance from abroad, recognising the work we do and that they want to continue collaborating. These academic networks can therefore provide an alternative to the political networks, and help to smooth waters. So the message was one of hope and determination, despite the disappointment.

Parliamentary Links Day 2.jpg

All emphasised that we now need to shout loud to ensure that science is prominent in the negotiations and in particular that the government maintain our overall investment in science. MPs assured us that they will do their best to fight for these things, and they said that we also need to send out the message to connections and networks across the world, that despite this decision Britain is a willing collaborator and welcoming society. Finally, they asked us to think about what we can learn. Although leaving the EU would clearly be bad for science, half of the public still responded with the leave vote. This suggests that science is not important to them, so what can we do now to convince people that science is worth investing in?

I will always remember this day at such an important time in British history. After all the hope given I look forward to seeing what the future holds for UK science!

Amber Abernethie is in the second year of her PhD in Cardiovascular Biology. She is based at the Queens Medical Research Centre (University of Edinburgh) but is originally from Cleethorpes, England.

Following the referendum result on the UK’s membership of the European Union (EU) the Society for Endocrinology urges the UK government to ensure that free movement of students, researchers and clinicians between the UK and other EU countries and full access to, and participation in, the EU research infrastructure is preserved.  We strongly believe that the free movement of labour is essential to the delivery of care within the National Health Service (NHS) and to ensure that the UK continues to be a world leader in international scientific research. The full statement is available on our website.

Categories Events, Membership, Public Engagement•Tags brexit, current affairs, Education, members, Parliament, parliamentary links day, research, the future

Getting the message out: anti-doping in sport

Published on 07/07/201617/02/2017 by Society for EndocrinologyLeave a comment

Next Tuesday, Liverpool John Moores University will host a public awareness day on anti-doping in sport, aimed predominantly at high school students, their teachers and practising coaches. In this post, Professor Graeme Close explains why it’s important to get an anti-doping message out to schools. The event is supported by a Society for Endocrinology public engagement grant.

Athletes who dope fall into two broad categories. Firstly, those who believe that it is not possible to be successful in their sport without using performance enhancing drugs and secondly those who accidentally take contaminated supplements or over-the-counter medication that contains prohibited substances. Without doubt, the best way to tackle both of these mistakes is by effectively educating athletes in schools before mistakes are made. In wake of recent doping scandals, this Society for Endocrinology sponsored event is not only timely but essential to promote clean sport.

We want attendees to think about why athletes do not need to dope in sport. We will cover the science of muscle mass and strength increases, which is very poorly understood. Many junior athletes believe that the only way to increase lean mass is to use sports supplements and/or take prohibited substances. In reality, this goal can be achieved through correct nutrition and optimisation of training plans. The problem is that many people do not understand how to eat and how to train to gain muscle mass and as such their training is often ineffective.

It is important to tell the truth about sports supplementation. There is currently a trend that you either have to join a “no-supplement” or “pro-supplement” team and there is no place for a balanced opinion. The reality is that there are a handful of supplements that may be beneficial if taken at the right time. If we are truthful with our education, athletes will come to qualified people for advice, such as nutritionists on the Sport and Exercise Nutrition register (SENr). In contrast, if we have a blanket no-supplement policy the danger is that athletes may take the matter into their own hands and take supplements that not only do not work but more worryingly have not been tested for contaminants.

As sport scientists, it is our moral and ethical duty to educate athletes on doping. It is crucial that respected practitioners and academics provide appropriate education with regards to anti-doping. As well as facing a potential lifetime ban from sport, there are many dangerous consequences of taking performance enhancing drugs such as cardiac damage and mental health problems. There are even fatalities following the misuse of drugs in sport.

The event we are hosting at LJMU will include highly experienced researchers and practitioners who support some of the world’s greatest athletes, as well as top level athletes themselves. In addition, the Rugby Football Union and UK Anti-Doping will be present to help us reach out to kids more effectively.

We hope that this is the first of many such educational days and that the students, teachers and coaches will leave the event feeling inspired and motivated to commit to a future of clean sport.

Public engagement grants have been developed to help Society members and public engagement professionals (non-members) organise and deliver outreach activities, aimed at school children and/or the general public, to communicate the science of endocrinology. Find out how to apply for a public engagement grant on the Grants page of our website.

Categories Grants & Prizes, Public Engagement•Tags anti-doping, Education, high school, John Moores, Liverpool, science comms, sports

International Thyroid Awareness Week 2016

Published on 25/05/201607/07/2016 by Society for EndocrinologyLeave a comment

JOE cover

The syndromes associated with a dysfunctional thyroid gland can have severe impacts on an individual’s quality of life. Consequently, research aimed at understanding normal thyroid function and how this deteriorates through the pathologies of the various thyroid-related conditions is a high priority.

To support Thyroid Awareness Week on 23-29 May we have created a collection of recently published papers from Society for Endocrinology journals. They’ve all got a thyroid focus and they are all free to download until the end of the month.

  • TERT promoter mutations in thyroid cancer Liu & Xing. Endocrine-Related Cancer (2016) 23 R143-R155.
  • Variation in the biochemical response to L-thyroxine therapy and relationship with peripheral thyroid hormone conversion efficiency Midgley et al. Endocrine Connections (2015) 4 196-205.
  • Thyroid hormone and vitamin D regulate VGF expression and promoter activity Lewis et al. Journal of Molecular Endocrinology (2015) 56 123-134.
  • Germline PARP4 mutations in patients with primary thyroid and breast cancers Ikeda et al. Endocrine-Related Cancer (2016) 23 171-179.
  • Polymorphism of IL37 gene as a protective factor for autoimmune thyroid disease Yan et al. Journal of Molecular Endocrinology (2015) 55 209-218.
  • A model for chronic, intrahypothalamic thyroid hormone administration in rats Zhang et al. Journal of Endocrinology (2016) 229 37-45.
  • Effects of maternal nicoting exposure on thyroid hormone metabolism and function in adult rat progeny Lisboa et al. Journal of Endocrinology (2015) 224 315-325.
  • Characterization of human follicular thyroid cancer cell lines in preclinical mouse models by Ashley N Reeb, Andrea Ziegler and Reigh-Yi Lin. Endocrine Connections (2016) 5 47-54.

 

If you’re a paid member of the Society for Endocrinology, you get free access to all journal content. So once you’ve read the papers above, just keep going. Remember to enter through the member section of our website to get access for free.

[And if you’re not a member, why not join us?]

Categories Public Engagement, Publishing•Tags clinical, free access, Publishing, research, thyroid, ThyroidAwarenessWeek

Lessons in Public Engagement

Published on 21/04/201614/04/2016 by Society for EndocrinologyLeave a comment

In our last public engagement post, we shared a simple How-To graphic for one of our most successful public engagement activities. Now, it’s time to see another:

Introducing: The Hormone Card Game

This is a great (and simple!) activity to use at science fairs, open days or even careers fairs.

Create a set of 10 cards – 5 of them show the name of a hormone, and the other 5 show a description of the function of each hormone. We printed ours on A4 card. When the cards have then been shuffled, participants have the task of matching each hormone to its correct function. For extra help, you can add clues to the back of the hormone cards – if the participants are unsure, they can turn over for a helpful hint.

Finally, what’s really great about this activity is that it provides an easy and engaging springboard for discussing hormones in a little more detail. Have a look below to see how it works:

Hormones Card Game_Infographic

Categories Events, Public Engagement•Tags Activity, Education, Game, How To, Science Fair

Life at the Big Bang: Lessons in Public Engagement

Published on 24/03/201631/03/2016 by Society for EndocrinologyLeave a comment

Last week was the Big Bang Fair 2016, and we were there in force at the NEC, Birmingham with our banners and our many, many test tubes of fake blood. And the crowds? They were BIG.

The aim of the game was to do exactly what our slogan said – Let’s Talk About Hormones! Over the next few posts, we’re going to tell you exactly how we did this, starting with this simple step-by-step instruction sheet for our most popular public engagement activity.

blood-sugar-test_pe (3)

Check out our Facebook page for a few photos from the Big Bang Fair, or try #BigBangFair on Twitter!

 

 

 

Image•Categories Events, Public Engagement•Tags Big Bang, Blood Sugar, Education, How To, Science Fair

Rare Disease Day: improving patient outcomes for rare endocrine diseases

Published on 29/02/201606/02/2018 by Society for Endocrinology1 Comment

Rare Disease Day takes place on the last day of February each year. With this in mind, we bring you a new post focusing on congenital adrenal hyperplasia (CAH). This is a rare endocrine condition affecting only around 1 in 14,000 births, and a focus for a UK-wide Society-led project to develop clinical outcomes and treatment for CAH patients.

RareDiseaseDay

CAH Adult Study Exercise (CaHASE) is one of five research and audit projects which the committee works on with the Society’s UK-wide network of members. The study aims to address clinical outcomes, quality of life and sexual function in adults with CAH.

CAH is one of the most common inherited diseases and is associated with enlarged (hyperplasic) adrenal glands, cortisol-deficiency and overproduction of androgen. Consequently, patients may have an inability to respond effectively to stress, a lowered metabolic efficiency and early or inappropriate sexual development. See our public-facing website, You and Your Hormones, for more information on the causes, symptoms and treatment of CAH.

CaHASE, set up in 2004, is led by Society member Professor Richard Ross, Head of the Unit of Diabetes and Endocrinology at the University of Sheffield.

“Most of the published literature on CAH is centred on CAH in childhood,” says Richard, “But with the development of advanced hormone treatment in the 50s, many patients now live into adulthood. We had a feeling these adults needed better care – so we set up CaHASE to look at how well they were being treated.”

Since the project was set up, a great deal has been invested in the development of CaHASE. Through our extensive member network, over 200 patients were recruited into the largest study ever of adults with CAH, the results of which demonstrated that new treatments were required. The study has provided a wealth of peer-reviewed literature which has fed directly into clinical practice at participating centres. For example, in Oxford, clinicians managed to bring back the majority of CAH patients who had been lost to follow-up, reducing ‘did not attend’ rates and expanding the number of CAH patients they see.

When asked what he hopes CaHASE will achieve in the future, Richard said, “It will continue to inform and develop clinical practice. We hope to bring new therapies to patients and improve the quality of life of those patients.”

CaHASE is one five projects supported and developed by our Society Clinical Committee: read an overview on these projects in the latest edition of the Society magazine, The Endocrinologist. We are proud to support Rare Disease Day in its aim to raise awareness amongst the general public and decision-makers about rare diseases and their impact on patients’ lives. The political momentum resulting from Rare Disease Day also serves advocacy purposes, aiming to contribute to the advancement of national plans and policies for rare diseases in a number of countries.

 

The Society for Endocrinology is a member of Rare Disease UK – the organisation coordinating Rare Disease Day.

Follow Rare Disease Day on Twitter using the hashtag #RareDiseaseDay

Categories Events, Public Engagement

2015 in review: ten endocrinology stories that got the world talking (part 2)

Published on 22/12/201516/11/2016 by omarjamshedLeave a comment

Welcome to the second part of our endocrine news stories countdown. The next five stories are the ones that truly got the world talking, chalking up a combined total of at least 4,000 news articles across the World Wide Web and splashing countless front pages of newspapers around the world.

Last_chance_for_a_suntan_-_Weymouth_-_geograph.org.uk_-_1491983

Continue reading “2015 in review: ten endocrinology stories that got the world talking (part 2)” →

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