There are currently 422 million people in the world who have diabetes – about 0.6% of the world’s population.
This figure is expected to double in the next 20 years.
In light of this alarming trend, the World Health Organization is dedicating 2016 World Health Day: Beat Diabetes to raising awareness of this life-threatening condition. Here are the basic stats:
Diabetes is an endocrine disease. So, to mark World Health Day, we have created a collection of recent, high-impact diabetes articles and made them all free to read – for the next two weeks. So have a browse below and find out how science is bringing the fight to diabetes!
Journal of Endocrinology:
Current understanding of metformin effect on the control of hyperglycemia in diabetes Hongying An & Ling He.
Lack of glucagon receptor signaling and its implications beyond glucose homeostasis Maureen J Charron and Patricia M Vuguin.
Defective insulin secretion by chronic glucagon receptor activation in glucose intolerant mice Linda Ahlkvist et al.
Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice Sofianos Andrikopoulos et al.
Increased Slc12a1 expression in β-cells and improved glucose disposal in Slc12a2 heterozygous mice Saeed Alshahrani et al.
Journal of Molecular Endocrinology:
Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes Sumaira Z Hasnain, Johannes B Prins and Michael A McGuckin.
Non-coding genome functions in diabetes Inês Cebola and Lorenzo Pasquali.
miR-410 enhanced hESC-derived pancreatic endoderm transplant to alleviate gestational diabetes mellitus Yang Mi et al.
Inhibition of 11β-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice Leping Zhao et al.
Demethylation of the MafB promoter in a compromised β-cell model Wataru Nishimura et al.
Endocrine Connections:
Update on strategies limiting iatrogenic hypoglycemia Aldo Bonaventura, Fabrizio Montecucco and Franco Dallegri.
Central and peripheral pathogenetic forms of type 2 diabetes: a proof-of-concept study Dmitry M Davydov and Malik K Nurbekov.
Lower fasting blood glucose in neurofibromatosis type 1 Aline Stangherlin Martins et al.
Gut microbiota and diet in patients with different glucose tolerance Lilit Egshatyan et al.
Mendelian randomization studies of biomarkers and type 2 diabetes Ali Abbasi.
Endocrinology, Diabetes & Metabolism Case Reports:
A silent myocardial infarction in the diabetes outpatient clinic: case report and review of the literature M S Draman et al.
Severe hypercalcemia and hypernatremia in a patient treated with canagliflozin Arshpreet Kaur and Stephen J Winters
Spontaneous diabetic myonecrosis: report of four cases from a tertiary care institute Soham Mukherjee et al.
One year remission of type 1 diabetes mellitus in a patient treated with sitagliptin Marcos M Lima-Martínez et al.
Suspension of basal insulin to avoid hypoglycemia in type 1 diabetes treated with insulin pump Mauro Boronat
As a Consultant Endocrinologist at University College Hospital in London, Professor Nick Finer treats patients affected by diabetes and its complications. Here, Nick describes the progress that has been made during his career and his thoughts on the future of diabetes.
The Endocrine Post 